Cognitive decline with chronic meningitis secondary to a COX-2 inhibitor
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چکیده
منابع مشابه
Cognitive decline with chronic meningitis secondary to a COX-2 inhibitor.
Non-steroidal anti-inflammatory drugs are currently being investigated as agents to reduce the incidence and progression of Alzheimer's disease. Paradoxically they have also been reported to induce deleterious effects on the central nervous system, including aseptic meningitis and cognitive decline in the elderly. We report a case of a 72-year-old woman who presented with a 6-week history of pr...
متن کاملCOX-2 inhibitor.
he developed severe psoriasis responsive only to repeated courses of the then newly available PUVA (psoralen plus UVA radiation) therapy. Between 1973 and 1993 he received PUVA once a week. During treatment no genital protection was used although he had never received UV therapy directly to the genital area. Two years after the onset of psoriasis he developed peripheral inflammatory arthritis. ...
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In addition to the well-established pathophysiological role that COX-2 plays in inflammation, recent evidence implies that this isoform may also be involved in multiple biologic events throughout the tumorigenic process. Many epidemiological studies demonstrate that nonsteroidal anti-inflammatory drugs (NSAIDs) reduce the risk of a wide range of tumors. Further, COX-2 is chronically overexpress...
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Retropharyngeal abscess is less frequently seen now as compared to few years ago , yet we have come across this case of a retropharyngeal abscess.All the clinical features suggested a child with meningitis but later on after investigating throughly he was found out to be having a retropharyngeal abcess. Hence, this attempt to report and record a case of retropharyngeal abscess secondary to vert...
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Cyclooxygenase 2 (COX-2) inhibitors are promising antiangiogenic agents in several preclinical models. The aim of the present study was to evaluate the effect of selective COX-2 inhibitors on vascular endothelial growth factor (VEGF) production in vitro and angiogenesis and growth of pancreatic cancer in vivo, focusing on putative differences between COX-2-negative and COX-2-positive tumors. VE...
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ژورنال
عنوان ژورنال: Age and Ageing
سال: 2004
ISSN: 0002-0729,1468-2834
DOI: 10.1093/ageing/afh112